01595nam a2200229Ia 4500 CTU_132098 210402s9999 xx 000 0 und d 2576000 615.1901 G787 Greaves, P Histopathology of preclinical toxicity studies : Interpretation and relevance in drug safety evaluation Peter Greaves Amsterdam Elsevier/AP 2007 This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology (Publisher description) Drugs,Laboratory animals,Động vật thí nghiệm,Thuốc Toxicity testing,Histopathology,Mô bệnh học,Thử nghiệm độc chất Huỳnh Mai Trung tâm Học liệu Trường Đại học Cần Thơ