01398nam a2200193Ia 4500 CTU_237037 210402s9999 xx 000 0 und d 612.45 A242 The adrenergic receptors : In the 21st century Edited by Dianne M. Perez. Totowa, N.J. Humana Press 2006 An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential gene therapy applications. The side-by-side comparison of all the adrenergic receptors (a1, a2, and b) provides the reader with an excellent survey of the field, including the rationale for designing better drugs to control blood pressure and heart function. Pharmacogenetics,Nguồn gốc của thuốc Tuyến Trung tâm Học liệu Trường Đại học Cần Thơ