01240nam a2200277Ia 4500 TVU_11016 210423s9999 xx 000 0 und d 019856922X 9780198569220 eng 612.8 J33 Vijg, Jan Aging of the genome The dual role of the DNA in life and death Jan Vijg Oxford,New York Oxford University Press 2007 x, 372 p. ill. 26 cm Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases Aging; Apoptosis; Genomes Jan Vijg Trung tâm Học liệu Trường Đại học Trà Vinh