01750nam a2200277Ia 4500 TVU_12498 210423s9999 xx 000 0 und d 0198509847 9780198509844 eng 616.075 M109 Pepe, Margaret Sullivan The Margaret Sullivan Pepe Oxford,New York Oxford University Press 2003 xvi, 302 p. ill. 25 cm Includes bibliographical references (p. 280-296) and index This book describes statistical concepts and techniques for evaluating medical diagnostic tests and biomarkers for detecting disease. More generally, the techniques pertain to the statistical classification problem for predicting a dichotomous outcome. Measures for quantifying test accuracy are described including sensitivity, specificity, predictive values, diagnostic likelihood ratios and the Receiver Operating Characteristic Curve that is commonly used for continuous and ordinal valued tests. Statistical procedures are presented for estimating and comparing them. Regression frameworks for assessing factors that influence test accuracy and for comparing tests while adjusting for such factors are presented. This book presents many worked examples of real data and should be of interest to practicing statisticians or quantitative researchers involved in the development of tests for classification or prediction in medicine Research Design; Diagnostic Techniques and Procedures; Statistics; Medical statistics; Diagnosis; Laboratory Margaret Sullivan Pepe Trung tâm Học liệu Trường Đại học Trà Vinh