MiRNA-Disease Associations Prediction based on Network Consistency Projection
The 11th Conference on Information Technology and its Applications; Topic: Data Science and AI; pp.23-32.
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Da Nang Publishing House
2022
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oai:elib.vku.udn.vn:123456789-23092023-09-25T22:32:04Z MiRNA-Disease Associations Prediction based on Network Consistency Projection Nguyen, Phuc Xuan Quynh Tran, Hoai Nhan Le, Anh Phuong MiRNA-disease Associations Prediction MDA Network Consistency Projection The 11th Conference on Information Technology and its Applications; Topic: Data Science and AI; pp.23-32. MicroRNAs (miRNAs) play an important role in the prevention, diagnosis, and treatment of human complex diseases. More and more experimental validated associations between miRNAs and diseases have been reported in recent studies, which provide useful information for new miRNA-disease association discovery. But through experiments, we have to overcome problems such as the inefficiency of methods, the need for a lot of manpower, materials, and finance… Therefore, reliable computational models are expected to be an effective supplement for inferring associations between miRNAs and diseases. In this paper, we propose a computational method based on network consistency projection to predict potential human miRNA-disease associations (MDA). This method enriches biological information and reduces prediction bias. Besides, it is not only a parameterless method but also does not require a negative sample. More importantly, it can predict miRNA without any known associated diseases. This method’s AUC value of 5-fold cross-validation (5-fold-CV) is also compared to five methods and it is shown that the AUC value of this method achieves the highest value. 2022-08-17T01:36:39Z 2022-08-17T01:36:39Z 2022-07 Working Paper 978-604-84-6711-1 http://elib.vku.udn.vn/handle/123456789/2309 en application/pdf Da Nang Publishing House |
| institution |
Trường Đại học Công nghệ Thông tin và Truyền thông Việt Hàn - Đại học Đà Nẵng |
| collection |
DSpace |
| language |
English |
| topic |
MiRNA-disease Associations Prediction MDA Network Consistency Projection |
| spellingShingle |
MiRNA-disease Associations Prediction MDA Network Consistency Projection Nguyen, Phuc Xuan Quynh Tran, Hoai Nhan Le, Anh Phuong MiRNA-Disease Associations Prediction based on Network Consistency Projection |
| description |
The 11th Conference on Information Technology and its Applications; Topic: Data Science and AI; pp.23-32. |
| format |
Working Paper |
| author |
Nguyen, Phuc Xuan Quynh Tran, Hoai Nhan Le, Anh Phuong |
| author_facet |
Nguyen, Phuc Xuan Quynh Tran, Hoai Nhan Le, Anh Phuong |
| author_sort |
Nguyen, Phuc Xuan Quynh |
| title |
MiRNA-Disease Associations Prediction based on Network Consistency Projection |
| title_short |
MiRNA-Disease Associations Prediction based on Network Consistency Projection |
| title_full |
MiRNA-Disease Associations Prediction based on Network Consistency Projection |
| title_fullStr |
MiRNA-Disease Associations Prediction based on Network Consistency Projection |
| title_full_unstemmed |
MiRNA-Disease Associations Prediction based on Network Consistency Projection |
| title_sort |
mirna-disease associations prediction based on network consistency projection |
| publisher |
Da Nang Publishing House |
| publishDate |
2022 |
| url |
http://elib.vku.udn.vn/handle/123456789/2309 |
| _version_ |
1849200728251301888 |