Mechanistic toxicology : The molecular basis of how chemicals disrupt biological targets

Boelsterli (University of Basel) describes the general principles that link xenobiotic-induced toxicity with the molecular pathways underlying the toxic effects. Topics addressed in the textbook include bioactivation of xenobiotics to reactive metabolites, xenobiotic-induced oxidative stress, and th...

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Detalles Bibliográficos
Autor Principal: Boelsterli, Urs A.
Formato: Libro
Idioma:Undetermined
Publicado: London Taylor & Francis 2002
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Descripción
Tóm tắt:Boelsterli (University of Basel) describes the general principles that link xenobiotic-induced toxicity with the molecular pathways underlying the toxic effects. Topics addressed in the textbook include bioactivation of xenobiotics to reactive metabolites, xenobiotic-induced oxidative stress, and the mechanisms of necrotic and apoptotic cell death.