Mechanistic toxicology : The molecular basis of how chemicals disrupt biological targets

Boelsterli (University of Basel) describes the general principles that link xenobiotic-induced toxicity with the molecular pathways underlying the toxic effects. Topics addressed in the textbook include bioactivation of xenobiotics to reactive metabolites, xenobiotic-induced oxidative stress, and th...

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Bibliografiske detaljer
Hovedforfatter: Boelsterli, Urs A.
Format: Bog
Sprog:Undetermined
Udgivet: London Taylor & Francis 2002
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Thư viện lưu trữ: Trung tâm Học liệu Trường Đại học Cần Thơ
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Summary:Boelsterli (University of Basel) describes the general principles that link xenobiotic-induced toxicity with the molecular pathways underlying the toxic effects. Topics addressed in the textbook include bioactivation of xenobiotics to reactive metabolites, xenobiotic-induced oxidative stress, and the mechanisms of necrotic and apoptotic cell death.