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Selected papers of Frederick Sanger : With commentaries

These papers are mainly concerned with the development of methods for "sequencing" - that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first p...

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Formato: Livro
Idioma:Undetermined
Publicado em: Singapore World Scientific 1996
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Thư viện lưu trữ: Trung tâm Học liệu Trường Đại học Cần Thơ
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Resumo:These papers are mainly concerned with the development of methods for "sequencing" - that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.