Genomic Perl : From bioinformatics basics to working code

In this introduction to computational molecular biology, Rex Dwyer explains many basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, he covers the biological background for each problem, develops a model for the...

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Tác giả chính: Dwyer, Rex A.
Định dạng: Sách
Ngôn ngữ:Undetermined
Được phát hành: Cambridge, UK Cambridge University Press 2003
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Thư viện lưu trữ: Trung tâm Học liệu Trường Đại học Cần Thơ
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Tóm tắt:In this introduction to computational molecular biology, Rex Dwyer explains many basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, he covers the biological background for each problem, develops a model for the solution, and then introduces the Perl concepts needed to implement the solution. The chapters discuss pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. Concrete examples and a step-by-step approach enable readers to grasp the computational and statistical methods.