Bioassay techniques for drug development

The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery....

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Định dạng: Sách
Ngôn ngữ:Undetermined
Được phát hành: Australia Harwood academic publishers 2001
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Thư viện lưu trữ: Trung tâm Học liệu Trường Đại học Cần Thơ
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245 0 |a Bioassay techniques for drug development 
245 0 |c Atta-ur-Rahman, M. Iqbal Choudhary, William J. Thomsen 
260 |a Australia 
260 |b Harwood academic publishers 
260 |c 2001 
520 |a The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The contents detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology. 
526 |a Thử nghiệm sinh học 
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650 |a Thuốc chống ung thư,Antineoplastic agents 
650 |x Nghiên cứu,Phương pháp luận,Research,Methodology 
910 |b dqhieu 
980 |a Trung tâm Học liệu Trường Đại học Cần Thơ