Production of succinic acid through overexpression of NAD(+)-dependent malic enzyme in an Escherichia coli mutant /

Míreanna Comhchosúla

• Expression of Ascaris suum malic enzyme in a mutant Escherichia coli allows production of succinic acid from glucose /
• A novel fermentation pathway in anEscherichia coli mutant producing succinic acid, acetic acid, and ethanol /
• Organic solvent tolerance and antibiotic resistance increased by overexpression of marA in Escherichia coli /
• Escherichia coli mutants resistant to inactivation by high hydrostatic pressure /
• High-level production of porphyrins in metabolically engineered escherichia coli : Systematic extension of a pathway assembled from overexpressed genes involved in heme biosynthesis /