The elimination of low-dose hyper-radiosensitivity by transfer of irradiated-cell conditioned medium depends on dose rate /

Míreanna Comhchosúla

• Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation /
• Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells /
• Dose-rate effectiveness for unstable-type chromosome aberrations detected in mice after continuous irradiation with low-dose-rate gamma rays /
• G2-phase chromosomal radiosensitivity of primary fibroblasts from hereditary retinoblastoma family members and some apparently normal controls /
• Clonally expanded T lymphocytes from atomic bomb survivors in vitro show no evidence of cytogenetic instability /