Viruses, genes, and cancer
This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor supp...
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| Format: | Book |
| Language: | Vietnamese |
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Switzerland
Springer
2017
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| Series: | Current topics in Microbiology and immunology
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| Subjects: | |
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| Institutions: | Thư viện Trường Đại học Nam Cần Thơ |
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| Summary: | This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor suppressor genes - in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. |
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| Physical Description: | xiii, 221 p. ill. 24cm |
| ISBN: | 9783319618036 |