Molecular toxicology

Molecular Toxicology reflects the revolution that toxicology has undergone in the last decade, as the molecular and genetic basis of the science--including drug metabolism, carcinogenesis, programmed cell death, and DNA repair--has been elucidated. It is the first text to explain the principles of t...

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Detalhes bibliográficos
Autor principal: Josephy, P. David
Outros Autores: P. David Josephy; Bengt Mannervik; Paul Ortiz de Montellano
Idioma:Undetermined
English
Publicado em: New York Oxford University Press 1997
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Thư viện lưu trữ: Trung tâm Học liệu Trường Đại học Trà Vinh
Descrição
Resumo:Molecular Toxicology reflects the revolution that toxicology has undergone in the last decade, as the molecular and genetic basis of the science--including drug metabolism, carcinogenesis, programmed cell death, and DNA repair--has been elucidated. It is the first text to explain the principles of toxicology in depth and from the perspective of modern biochemistry and molecular biology, while also providing a sense of the historical development of the science. Emphasizing the latest molecular biological approaches, the book covers xenobiotic biotransformation; reactive intermediates and their interactions with macromolecules; cloning, expression, and analysis of the enzymes of biotransformation; and molecular toxicology of aromatic amines, nitrosamines, polycyclic aromatic hydrocarbons, and chlorinated compounds. The toxicology of oxygen and oxidative stress is also covered in depth
Descrição Física:368 p.
ill.
26 cm
ISBN:0195093402
9780195093407