Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound

The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Five hundred and fifty eight Korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as...

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Những tác giả chính: Hoàng, Việt Bách Khoa, Lê, Bá Lê, Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: MDPI 2022
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Truy cập trực tuyến:http://scholar.dlu.edu.vn/handle/123456789/1019
https://doi.org/10.3390/molecules19033607
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Thư viện lưu trữ: Thư viện Trường Đại học Đà Lạt
id oai:scholar.dlu.edu.vn:123456789-1019
record_format dspace
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic periodonititis
Pittosporium tobira
natural products
R1-barrigenol
triterpene sapogenin
spellingShingle periodonititis
Pittosporium tobira
natural products
R1-barrigenol
triterpene sapogenin
Hoàng, Việt Bách Khoa
Lê, Bá Lê
Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
description The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Five hundred and fifty eight Korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as Porphyromonas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum. Among the various medicinal plants, the alcohol extract of Pittosporum tobira, which significantly exhibited antibacterial effect for all tested strains, showed the highest activity in the antimicrobial assays. NMR analyses revealed that R1-barrigenol, a triterpene sapogenin, was the most effective compound in P. tobira. These results demonstrated that P. tobira possesses antimicrobial properties and would be beneficial for the prevention and treatment of periodontitis.
format Journal article
author Hoàng, Việt Bách Khoa
Lê, Bá Lê
Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
author_facet Hoàng, Việt Bách Khoa
Lê, Bá Lê
Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
author_sort Hoàng, Việt Bách Khoa
title Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_short Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_full Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_fullStr Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_full_unstemmed Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_sort antimicrobial activities against periodontopathic bacteria of pittosporum tobira and its active compound
publisher MDPI
publishDate 2022
url http://scholar.dlu.edu.vn/handle/123456789/1019
https://doi.org/10.3390/molecules19033607
_version_ 1768305917841899520
spelling oai:scholar.dlu.edu.vn:123456789-10192022-09-15T05:45:57Z Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound Hoàng, Việt Bách Khoa Lê, Bá Lê Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee periodonititis Pittosporium tobira natural products R1-barrigenol triterpene sapogenin The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Five hundred and fifty eight Korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as Porphyromonas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum. Among the various medicinal plants, the alcohol extract of Pittosporum tobira, which significantly exhibited antibacterial effect for all tested strains, showed the highest activity in the antimicrobial assays. 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