Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound

The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Five hundred and fifty eight Korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as...

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Những tác giả chính:	Hoàng, Việt Bách Khoa, Lê, Bá Lê, Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	MDPI 2022
Những chủ đề:	periodonititis Pittosporium tobira natural products R1-barrigenol triterpene sapogenin
Truy cập trực tuyến:	http://scholar.dlu.edu.vn/handle/123456789/1019 https://doi.org/10.3390/molecules19033607
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Thư viện lưu trữ:	Thư viện Trường Đại học Đà Lạt

id	oai:scholar.dlu.edu.vn:123456789-1019
record_format	dspace
institution	Thư viện Trường Đại học Đà Lạt
collection	Thư viện số
language	English
topic	periodonititis Pittosporium tobira natural products R1-barrigenol triterpene sapogenin
spellingShingle	periodonititis Pittosporium tobira natural products R1-barrigenol triterpene sapogenin Hoàng, Việt Bách Khoa Lê, Bá Lê Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
description	The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Five hundred and fifty eight Korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as Porphyromonas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum. Among the various medicinal plants, the alcohol extract of Pittosporum tobira, which significantly exhibited antibacterial effect for all tested strains, showed the highest activity in the antimicrobial assays. NMR analyses revealed that R1-barrigenol, a triterpene sapogenin, was the most effective compound in P. tobira. These results demonstrated that P. tobira possesses antimicrobial properties and would be beneficial for the prevention and treatment of periodontitis.
format	Journal article
author	Hoàng, Việt Bách Khoa Lê, Bá Lê Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
author_facet	Hoàng, Việt Bách Khoa Lê, Bá Lê Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee
author_sort	Hoàng, Việt Bách Khoa
title	Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_short	Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_full	Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_fullStr	Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_full_unstemmed	Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound
title_sort	antimicrobial activities against periodontopathic bacteria of pittosporum tobira and its active compound
publisher	MDPI
publishDate	2022
url	http://scholar.dlu.edu.vn/handle/123456789/1019 https://doi.org/10.3390/molecules19033607
_version_	1768305917841899520
spelling	oai:scholar.dlu.edu.vn:123456789-10192022-09-15T05:45:57Z Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound Hoàng, Việt Bách Khoa Lê, Bá Lê Jung-Hyun Oh, Yong Joon Jeong, Hyun Jung Koo, Dae Won Park, Se Chan Kang,Joon Hyeong Cho, Jin-Yong Lee periodonititis Pittosporium tobira natural products R1-barrigenol triterpene sapogenin The study of medicinal plants for treatment of periodontitis is of great value to establish their efficacy as sources of new antimicrobial drugs. Five hundred and fifty eight Korean local plant extracts were screened for antibacterial activity against representative periodontopathic bacteria such as Porphyromonas gingivalis, Prevotella intermedia, and Fusobacterium nucleatum. Among the various medicinal plants, the alcohol extract of Pittosporum tobira, which significantly exhibited antibacterial effect for all tested strains, showed the highest activity in the antimicrobial assays. 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Antimicrobial Activities against Periodontopathic Bacteria of Pittosporum tobira and Its Active Compound

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