MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling
Mitsugumin 53 (MG53) negatively regulates skeletal myogenesis by targeting insulin receptor substrate 1 (IRS-1). Here, we show that MG53 is an ubiquitin E3 ligase that induces IRS-1 ubiquitination with the help of an E2-conjugating enzyme, UBE2H. Molecular manipulations that disrupt the E3-ligase...
में बचाया:
| मुख्य लेखक: | |
|---|---|
| स्वरूप: | Journal article |
| भाषा: | English |
| प्रकाशित: |
Springer
2022
|
| विषय: | |
| ऑनलाइन पहुंच: | http://scholar.dlu.edu.vn/handle/123456789/1569 |
| टैग : |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|
| Thư viện lưu trữ: | Thư viện Trường Đại học Đà Lạt |
|---|