UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam
Hedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-p...
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2023
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oai:scholar.dlu.edu.vn:123456789-20922023-04-29T07:51:47Z UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam Pham, Hong Ngoc Tran, Chieu An Trịnh, Thị Điệp Nguyen Thi, Ngoc Lan Tran Phan, Huynh Nhu Le, Van Nhan Le, Ngoc Hung Phung, Van Trung Hedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS/MS). MS, and MS/MS experiments were manipulated using both negative and positive ionization modes to provide molecular mass information and production spectra for the structural elucidation of compounds. A total of 46 compounds including 24 triterpene saponins and other compounds were successfully identified of which four established saponin structures have been reported for the first time. This study has provided a base for building a quality control of the raw materials according to the profile of triterpene saponins and assessment of pharmaceutical ingredients of H. helix planted in Vietnam. 2023-04-29T07:51:42Z 2023-04-29T07:51:42Z 2022 Journal article Bài báo đăng trên tạp chí thuộc SCOPUS, bao gồm book chapter 2090-8865 http://scholar.dlu.edu.vn/handle/123456789/2092 10.1155/2022/1167265 35979140 en Journal of analytical methods in chemistry 20908873 20908865 |
| institution |
Thư viện Trường Đại học Đà Lạt |
| collection |
Thư viện số |
| language |
English |
| description |
Hedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS/MS). MS, and MS/MS experiments were manipulated using both negative and positive ionization modes to provide molecular mass information and production spectra for the structural elucidation of compounds. A total of 46 compounds including 24 triterpene saponins and other compounds were successfully identified of which four established saponin structures have been reported for the first time. This study has provided a base for building a quality control of the raw materials according to the profile of triterpene saponins and assessment of pharmaceutical ingredients of H. helix planted in Vietnam. |
| format |
Journal article |
| author |
Pham, Hong Ngoc Tran, Chieu An Trịnh, Thị Điệp Nguyen Thi, Ngoc Lan Tran Phan, Huynh Nhu Le, Van Nhan Le, Ngoc Hung Phung, Van Trung |
| spellingShingle |
Pham, Hong Ngoc Tran, Chieu An Trịnh, Thị Điệp Nguyen Thi, Ngoc Lan Tran Phan, Huynh Nhu Le, Van Nhan Le, Ngoc Hung Phung, Van Trung UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| author_facet |
Pham, Hong Ngoc Tran, Chieu An Trịnh, Thị Điệp Nguyen Thi, Ngoc Lan Tran Phan, Huynh Nhu Le, Van Nhan Le, Ngoc Hung Phung, Van Trung |
| author_sort |
Pham, Hong Ngoc |
| title |
UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_short |
UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_full |
UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_fullStr |
UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_full_unstemmed |
UHPLC-Q-TOF-MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_sort |
uhplc-q-tof-ms/ms dereplication to identify chemical constituents of hedera helix leaves in vietnam |
| publishDate |
2023 |
| url |
http://scholar.dlu.edu.vn/handle/123456789/2092 |
| _version_ |
1768306352647569408 |