Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam

New essential oils (EOs) extracted from different parts of two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam were investigated for their chemical composition, anti-inflammatory and cytotoxic activity. Sixty-nine total compounds were identified in the EOs by GC/MS. The major constitu...

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Những tác giả chính: Trịnh, Thị Điệp, Lương, Văn Dũng, Nguyễn, Thị Tố Uyên, Phung, Van Trung, Trần, Thị Hoài Linh, Huỳnh, Thanh Trúc, Dang, Vinh Khai, Lê, Thị Thanh Trân, Nguyen, Thi Hoai, Do, Thi Thao
Định dạng: Research article
Ngôn ngữ:English
Được phát hành: Taylor & Francis 2023
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Truy cập trực tuyến:https://scholar.dlu.edu.vn/handle/123456789/3036
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spelling oai:scholar.dlu.edu.vn:123456789-30362024-06-15T08:44:27Z Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam Trịnh, Thị Điệp Lương, Văn Dũng Nguyễn, Thị Tố Uyên Phung, Van Trung Trần, Thị Hoài Linh Huỳnh, Thanh Trúc Dang, Vinh Khai Lê, Thị Thanh Trân Nguyen, Thi Hoai Do, Thi Thao Luvunga scandens Luvunga hongiaoensis essential oil GC/MS NO inhibition cytotoxicity New essential oils (EOs) extracted from different parts of two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam were investigated for their chemical composition, anti-inflammatory and cytotoxic activity. Sixty-nine total compounds were identified in the EOs by GC/MS. The major constituent of the leaf, fruit, and root EOs from L. scandens was β-caryophyllene (71.5%, 63.0%, and 31.5% respectively). The main compounds in L. hongiaoensis EOs were β-elemene (34.3% in leaf oil) and caryophyllene oxide (21.2% in root oil, 19.4% in stem oil). The EO from L. scandens fruits significantly inhibited nitric oxide production on LPS-induced RAW264.7 cells (IC50 = 37.95±2.76 g/mL). The EOs from L. hongiaoensis roots and L. scandens leaves and fruits exhibited cytotoxic activity against MCF-7, SK-LU-1, and HepG2 (IC50 from 49.74±3.36 to 97.82±8.61 g/mL). This is the first report on L. hongiaoensis EOs and significantly complements the composition and bioactivity of L. scandens EOs. 38 11 1834-1843 2023-10-02T09:44:40Z 2023-10-02T09:44:40Z 2024 Research article Bài báo đăng trên tạp chí thuộc ISI, bao gồm book chapter https://scholar.dlu.edu.vn/handle/123456789/3036 10.1080/14786419.2023.2225125 en Đề tài KHCN cấp Bộ Natural Product Research 1478-6427 B2022-CT562-06 Taylor & Francis
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic Luvunga scandens
Luvunga hongiaoensis
essential oil
GC/MS
NO inhibition
cytotoxicity
spellingShingle Luvunga scandens
Luvunga hongiaoensis
essential oil
GC/MS
NO inhibition
cytotoxicity
Trịnh, Thị Điệp
Lương, Văn Dũng
Nguyễn, Thị Tố Uyên
Phung, Van Trung
Trần, Thị Hoài Linh
Huỳnh, Thanh Trúc
Dang, Vinh Khai
Lê, Thị Thanh Trân
Nguyen, Thi Hoai
Do, Thi Thao
Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam
description New essential oils (EOs) extracted from different parts of two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam were investigated for their chemical composition, anti-inflammatory and cytotoxic activity. Sixty-nine total compounds were identified in the EOs by GC/MS. The major constituent of the leaf, fruit, and root EOs from L. scandens was β-caryophyllene (71.5%, 63.0%, and 31.5% respectively). The main compounds in L. hongiaoensis EOs were β-elemene (34.3% in leaf oil) and caryophyllene oxide (21.2% in root oil, 19.4% in stem oil). The EO from L. scandens fruits significantly inhibited nitric oxide production on LPS-induced RAW264.7 cells (IC50 = 37.95±2.76 g/mL). The EOs from L. hongiaoensis roots and L. scandens leaves and fruits exhibited cytotoxic activity against MCF-7, SK-LU-1, and HepG2 (IC50 from 49.74±3.36 to 97.82±8.61 g/mL). This is the first report on L. hongiaoensis EOs and significantly complements the composition and bioactivity of L. scandens EOs.
format Research article
author Trịnh, Thị Điệp
Lương, Văn Dũng
Nguyễn, Thị Tố Uyên
Phung, Van Trung
Trần, Thị Hoài Linh
Huỳnh, Thanh Trúc
Dang, Vinh Khai
Lê, Thị Thanh Trân
Nguyen, Thi Hoai
Do, Thi Thao
author_facet Trịnh, Thị Điệp
Lương, Văn Dũng
Nguyễn, Thị Tố Uyên
Phung, Van Trung
Trần, Thị Hoài Linh
Huỳnh, Thanh Trúc
Dang, Vinh Khai
Lê, Thị Thanh Trân
Nguyen, Thi Hoai
Do, Thi Thao
author_sort Trịnh, Thị Điệp
title Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam
title_short Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam
title_full Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam
title_fullStr Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam
title_full_unstemmed Chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two Luvunga species (L. scandens and L. hongiaoensis) from Vietnam
title_sort chemical composition, anti-inflammatory and cytotoxic activity of essential oils from two luvunga species (l. scandens and l. hongiaoensis) from vietnam
publisher Taylor & Francis
publishDate 2023
url https://scholar.dlu.edu.vn/handle/123456789/3036
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