Lyme Disease An Evidence-based Approach

Spirochaetal infections somehow seem to take on larger-than-life roles. ‘The French disease’, a.k.a. syphilis, assumed almost mythic proportions. Initially brought back from the New World to the Old, perhaps as divine retribution for measles, smallpox and myriad other curses visited on North A...

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Tác giả chính: Halperin, John J
Định dạng: Sách
Ngôn ngữ:English
Được phát hành: CABI 2014
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Truy cập trực tuyến:https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/37056
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spelling oai:scholar.dlu.edu.vn:DLU123456789-370562023-11-11T05:28:29Z Lyme Disease An Evidence-based Approach Halperin, John J Approach Disease Spirochaetal infections somehow seem to take on larger-than-life roles. ‘The French disease’, a.k.a. syphilis, assumed almost mythic proportions. Initially brought back from the New World to the Old, perhaps as divine retribution for measles, smallpox and myriad other curses visited on North America’s aboriginal populations by European conquerors, neurosyphilis aff ected so many historic personalities as to give it a legitimate claim as a molder of history. Even early in the 20th century, a lack of understanding of the pathophysiology of many other diseases led to the at ribution of all manner of disorders to this infection, ot en by default, because nobody could come up with a bet er explanation. Early in the history of Lyme disease, many latched on to the syphilis parallel, asserting that this new spirochaetosis, like its cousin, could masquerade as innumerable other ailments. However, the greatest similarity between the two has been the tendency to inappropriately at ribute unrelated, but otherwise not readily explained, disorders to the unjustly accused spirochaete. The past decade or two has seen medicine move broadly and strongly towards the requirement for evidence-based support for its conclusions and actions. For those of us over a certain age, although this is certainly intellectually satisfying, it produces a distinct cognitive dissonance. When I was a resident, the truth was what the professors said and wrote in textbooks. The evidence basis at best consisted of case series and anecdotal observations. Unfortunately, even the most brilliant minds, individuals who led medicine for decades, were ot en proved wrong as new technologies – imaging, biochemical assays, DNA analysis or whatever – provided more powerful tools to answer questions. 2014-04-23T01:40:51Z 2014-04-23T01:40:51Z 2011 Book 978 1 84593 804 8 https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/37056 en application/pdf CABI
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic Approach
Disease
spellingShingle Approach
Disease
Halperin, John J
Lyme Disease An Evidence-based Approach
description Spirochaetal infections somehow seem to take on larger-than-life roles. ‘The French disease’, a.k.a. syphilis, assumed almost mythic proportions. Initially brought back from the New World to the Old, perhaps as divine retribution for measles, smallpox and myriad other curses visited on North America’s aboriginal populations by European conquerors, neurosyphilis aff ected so many historic personalities as to give it a legitimate claim as a molder of history. Even early in the 20th century, a lack of understanding of the pathophysiology of many other diseases led to the at ribution of all manner of disorders to this infection, ot en by default, because nobody could come up with a bet er explanation. Early in the history of Lyme disease, many latched on to the syphilis parallel, asserting that this new spirochaetosis, like its cousin, could masquerade as innumerable other ailments. However, the greatest similarity between the two has been the tendency to inappropriately at ribute unrelated, but otherwise not readily explained, disorders to the unjustly accused spirochaete. The past decade or two has seen medicine move broadly and strongly towards the requirement for evidence-based support for its conclusions and actions. For those of us over a certain age, although this is certainly intellectually satisfying, it produces a distinct cognitive dissonance. When I was a resident, the truth was what the professors said and wrote in textbooks. The evidence basis at best consisted of case series and anecdotal observations. Unfortunately, even the most brilliant minds, individuals who led medicine for decades, were ot en proved wrong as new technologies – imaging, biochemical assays, DNA analysis or whatever – provided more powerful tools to answer questions.
format Book
author Halperin, John J
author_facet Halperin, John J
author_sort Halperin, John J
title Lyme Disease An Evidence-based Approach
title_short Lyme Disease An Evidence-based Approach
title_full Lyme Disease An Evidence-based Approach
title_fullStr Lyme Disease An Evidence-based Approach
title_full_unstemmed Lyme Disease An Evidence-based Approach
title_sort lyme disease an evidence-based approach
publisher CABI
publishDate 2014
url https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/37056
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