Parasitic Nematodes Molecular Biology, Biochemistry and Immunology (2nd Edition)
The pace of advances in research into parasitic nematodes continues to accelerate, and there is a degree of interplay of ideas, techniques and analytical approaches amongst researchers work- ing on parasites of humans, animals, plants, and free-living species that is equalled in few if any fiel...
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| Những tác giả chính: | , |
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
| Được phát hành: |
CABI
2014
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| Những chủ đề: | |
| Truy cập trực tuyến: | https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/37188 |
| Các nhãn: |
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| Thư viện lưu trữ: | Thư viện Trường Đại học Đà Lạt |
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| Tóm tắt: | The pace of advances in research into parasitic nematodes continues to accelerate, and there is
a degree of interplay of ideas, techniques and analytical approaches amongst researchers work-
ing on parasites of humans, animals, plants, and free-living species that is equalled in few if any
fields of infection biology. The potential benefits from such interactions have never been in doubt,
but these benefits are now being fulfilled at an increasing pace, allowing new unifying principles
to develop. For example, it is entirely possible that nematodes infecting humans and those infect-
ing plants could be using similar or related means by which to modify the tissues and immunologi-
cal defences of their hosts. In this, the breadth and depth of what has been achieved with the
free-living Caenorhabditis elegans continues to provide a strong link between all branches of
nematode parasitology, but it is becoming clear that this is not merely a one-way process. The
vast amount of information now arising from genomics, transcriptomics and proteomics of nema-
todes is opening up new worlds, especially when one considers how diverse are the lifestyles of
nematodes, and that there are arguably more species of nematode than in any other metazoan
phylum. Moreover, the integration of these data with the immunology of infection is proceeding
at a remarkable pace, revealing the common and distinctive ways in which nematodes control
their tissue and immune system environments, and the molecules they use to do so. The effects
of nematode infection on the immune system continue to bring forth new surprises including
understanding the functions and behaviours of previously somewhat mysterious cell types and
tissue responses - the understanding of the functions of Th2 immune responses and alternatively
activated macrophages are cases in point.
In compiling this book we set out to illustrate the scope and dynamism of the subject area,
knowing that it would be impossible to represent it all. So, we invited authors scattered widely across
nematode parasitology and biology, selecting those who were strongly research active, of interna-
tional standing, and with vision beyond their immediate subject areas. We asked them to choose a
subject close to them, to introduce and develop it in their writing, but then also to extend their think-
ing into speculative areas that might be struck out by reviewers and editors of journals publishing
primary research. Scientists can become conservative in their writing, but without extended and
over-the-horizon thinking, new approaches and ideas will not make an appearance. |
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