Photopolymerizable Porous Polyorganophosphazenes (Degradable Matrices for Tissue Engineering)
Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry f...
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Tác giả chính: | |
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Định dạng: | Sách |
Ngôn ngữ: | English |
Được phát hành: |
2015
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Những chủ đề: | |
Truy cập trực tuyến: | https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/56083 |
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Thư viện lưu trữ: | Thư viện Trường Đại học Đà Lạt |
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Tóm tắt: | Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type. |
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