Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing

Laboratory in-vitro models that mimic in-vivo conditions to follow the response of cells to changes in their micro-environment, including treatment with drugs and toxic compounds, is still a challenging and demanding aim for scientists. In particular for drug research it is very important to kno...

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Đã lưu trong:
Chi tiết về thư mục
Tác giả chính: Alborzinia, Hamed
Định dạng: Sách
Ngôn ngữ:English
Được phát hành: Springer 2015
Những chủ đề:
Truy cập trực tuyến:https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/56109
Các nhãn: Thêm thẻ
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Miêu tả
Tóm tắt:Laboratory in-vitro models that mimic in-vivo conditions to follow the response of cells to changes in their micro-environment, including treatment with drugs and toxic compounds, is still a challenging and demanding aim for scientists. In particular for drug research it is very important to know all the effects that can be triggered in mammalian cells when exposed to a bioactive, potential drug or toxic compound. Such a system will be very useful in the field of medicinal chemistry as well as for pharmaceutical companies. Newly synthesized compounds designed for therapeutic applications may not only act on their designated targets, but rather interfere with various biochemical pathways, which could have negative and beneficial impact on their application. These effects have to be carefully monitored before drugs can be used in therapeutic applications in the clinic...