Mass Spectrometry Imaging of Small Molecules
In the field of small-molecule studies, vast efforts have been put forth in order to comprehensively characterize and quantify metabolites formed from complex mechanistic pathways within biochemical and biological organisms. Many technologies and methodologies have been developed to aid understandi...
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| Tác giả chính: | |
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| Định dạng: | Sách |
| Ngôn ngữ: | English |
| Được phát hành: |
Humana Press
2015
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| Những chủ đề: | |
| Truy cập trực tuyến: | https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/57224 |
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| Thư viện lưu trữ: | Thư viện Trường Đại học Đà Lạt |
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| Tóm tắt: | In the field of small-molecule studies, vast efforts have been put forth in order to comprehensively characterize and quantify metabolites formed from complex mechanistic pathways within biochemical and
biological organisms. Many technologies and methodologies have been developed to aid understanding
of the inherent complexities within biological metabolomes. Specifically, mass spectroscopy imaging
(MSI) has emerged as a foundational technique in gaining insight into the molecular entities within
cells, tissues, and whole-body samples. In this chapter we provide a brief overview of major technical
components involved in MSI, including topics such as sample preparation, analyte ionization, ion detection, and data analysis. Emerging applications are briefly summarized as well, but details will be presented in the following chapters... |
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