Mathematical Modelling of Chromosome Replication and Replicative Stress
DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of...
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2015
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oai:scholar.dlu.edu.vn:DLU123456789-576182023-11-11T05:45:15Z Mathematical Modelling of Chromosome Replication and Replicative Stress Karschau, Jens DNA replication Mathematical models Physics Physics of the Cell DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive. This work makes important contributions to this line of research. In particular, it addresses two key questions in the area of DNA replication: which evolutionary forces drive the positioning of replication origins in the chromosome and how is the spatial organization of replication factories achieved inside the nucleus of a cell?. 2015-08-19T03:20:07Z 2015-08-19T03:20:07Z 2015 Book 978-3-319-08861-7 https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/57618 en application/pdf Springer |
| institution |
Thư viện Trường Đại học Đà Lạt |
| collection |
Thư viện số |
| language |
English |
| topic |
DNA replication Mathematical models Physics Physics of the Cell |
| spellingShingle |
DNA replication Mathematical models Physics Physics of the Cell Karschau, Jens Mathematical Modelling of Chromosome Replication and Replicative Stress |
| description |
DNA replication is arguably the most crucial process at work in living cells. It is the mechanism by which organisms pass their genetic information from one generation to the next and life on Earth would be unthinkable without it. Despite the discovery of DNA structure in the 1950s, the mechanism of its replication remains rather elusive.
This work makes important contributions to this line of research. In particular, it addresses two key questions in the area of DNA replication: which evolutionary forces drive the positioning of replication origins in the chromosome and how is the spatial organization of replication factories achieved inside the nucleus of a cell?. |
| format |
Book |
| author |
Karschau, Jens |
| author_facet |
Karschau, Jens |
| author_sort |
Karschau, Jens |
| title |
Mathematical Modelling of Chromosome Replication and Replicative Stress |
| title_short |
Mathematical Modelling of Chromosome Replication and Replicative Stress |
| title_full |
Mathematical Modelling of Chromosome Replication and Replicative Stress |
| title_fullStr |
Mathematical Modelling of Chromosome Replication and Replicative Stress |
| title_full_unstemmed |
Mathematical Modelling of Chromosome Replication and Replicative Stress |
| title_sort |
mathematical modelling of chromosome replication and replicative stress |
| publisher |
Springer |
| publishDate |
2015 |
| url |
https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/57618 |
| _version_ |
1782534986068393984 |