Holographic Sensors
This thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions. Developing non-invasive and reusable diagnostics sensors that can be eas...
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2015
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oai:scholar.dlu.edu.vn:DLU123456789-577262023-11-11T05:50:41Z Holographic Sensors Yetisen, Ali Kemal Chemistry Holography Biosensors This thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions. Developing non-invasive and reusable diagnostics sensors that can be easily manufactured will support the monitoring of high-risk individuals in any clinical or point-of-care setting. Sensor fabrication approaches outlined include silver-halide chemistry, laser ablation and photopolymerization. The sensors employ off-axis Bragg diffraction gratings of ordered silver nanoparticles and localized refractive index changes in poly (2-hydroxyethyl methacrylate) and polyacrylamide films. The sensors exhibited reversible Bragg peak shifts, and diffracted the spectrum of narrow-band light over the wavelength range λpeak ≈ 495-1100 nm. Clinical trials of glucose sensors in the urine samples of diabetic patients demonstrated that they offer superior performance compared to commercial high-throughput urinalysis devices. Lastly, a generic smartphone application to quantify colorimetric tests was developed and tested for both Android and iOS operating systems. The sensing platform and smartphone application may have implications for the development of low-cost, reusable and equipment-free point-of-care diagnostic devices. 2015-08-24T02:26:13Z 2015-08-24T02:26:13Z 2015 Book 978-3-319-13584-7 https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/57726 en application/pdf Springer |
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Thư viện Trường Đại học Đà Lạt |
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Thư viện số |
language |
English |
topic |
Chemistry Holography Biosensors |
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Chemistry Holography Biosensors Yetisen, Ali Kemal Holographic Sensors |
description |
This thesis presents a theoretical and experimental approach for the rapid fabrication, optimization and testing of holographic sensors for the quantification of pH, organic solvents, metal cations, and glucose in solutions.
Developing non-invasive and reusable diagnostics sensors that can be easily manufactured will support the monitoring of high-risk individuals in any clinical or point-of-care setting. Sensor fabrication approaches outlined include silver-halide chemistry, laser ablation and photopolymerization. The sensors employ off-axis Bragg diffraction gratings of ordered silver nanoparticles and localized refractive index changes in poly (2-hydroxyethyl methacrylate) and polyacrylamide films. The sensors exhibited reversible Bragg peak shifts, and diffracted the spectrum of narrow-band light over the wavelength range λpeak ≈ 495-1100 nm. Clinical trials of glucose sensors in the urine samples of diabetic patients demonstrated that they offer superior performance compared to commercial high-throughput urinalysis devices. Lastly, a generic smartphone application to quantify colorimetric tests was developed and tested for both Android and iOS operating systems. The sensing platform and smartphone application may have implications for the development of low-cost, reusable and equipment-free point-of-care diagnostic devices. |
format |
Book |
author |
Yetisen, Ali Kemal |
author_facet |
Yetisen, Ali Kemal |
author_sort |
Yetisen, Ali Kemal |
title |
Holographic Sensors |
title_short |
Holographic Sensors |
title_full |
Holographic Sensors |
title_fullStr |
Holographic Sensors |
title_full_unstemmed |
Holographic Sensors |
title_sort |
holographic sensors |
publisher |
Springer |
publishDate |
2015 |
url |
https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/57726 |
_version_ |
1782538574778859520 |