Complex Structure and Dynamics of the Heart

This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to...

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Tác giả chính: Bittihn, Philip
Định dạng: Sách
Ngôn ngữ:English
Được phát hành: Springer 2016
Những chủ đề:
Truy cập trực tuyến:https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/59728
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spelling oai:scholar.dlu.edu.vn:DLU123456789-597282023-11-11T06:48:54Z Complex Structure and Dynamics of the Heart Bittihn, Philip Physiology Heart Mechanical properties This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock – currently the only reliable way to terminate life-threatening fibrillation – by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias. 2016-03-01T07:27:16Z 2016-03-01T07:27:16Z 2015 Book 978-3-319-12232-8 978-3-319-12231-1 https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/59728 en application/pdf Springer
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic Physiology
Heart
Mechanical properties
spellingShingle Physiology
Heart
Mechanical properties
Bittihn, Philip
Complex Structure and Dynamics of the Heart
description This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock – currently the only reliable way to terminate life-threatening fibrillation – by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.
format Book
author Bittihn, Philip
author_facet Bittihn, Philip
author_sort Bittihn, Philip
title Complex Structure and Dynamics of the Heart
title_short Complex Structure and Dynamics of the Heart
title_full Complex Structure and Dynamics of the Heart
title_fullStr Complex Structure and Dynamics of the Heart
title_full_unstemmed Complex Structure and Dynamics of the Heart
title_sort complex structure and dynamics of the heart
publisher Springer
publishDate 2016
url https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/59728
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