A Guide to Numerical Modelling in Systems Biology

This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for c...

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Những tác giả chính: Deuflhard, Peter, Röblitz, Susanna
Định dạng: Sách
Ngôn ngữ:English
Được phát hành: Springer 2016
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spelling oai:scholar.dlu.edu.vn:DLU123456789-598332023-11-11T06:53:08Z A Guide to Numerical Modelling in Systems Biology Deuflhard, Peter Röblitz, Susanna Differential equations Bioinformatics Mathematical models Systems biology This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included. 2016-03-15T07:53:19Z 2016-03-15T07:53:19Z 2015 Book 978-3-319-20059-0 978-3-319-20058-3 https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/59833 en application/pdf Springer
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic Differential equations
Bioinformatics
Mathematical models
Systems biology
spellingShingle Differential equations
Bioinformatics
Mathematical models
Systems biology
Deuflhard, Peter
Röblitz, Susanna
A Guide to Numerical Modelling in Systems Biology
description This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.
format Book
author Deuflhard, Peter
Röblitz, Susanna
author_facet Deuflhard, Peter
Röblitz, Susanna
author_sort Deuflhard, Peter
title A Guide to Numerical Modelling in Systems Biology
title_short A Guide to Numerical Modelling in Systems Biology
title_full A Guide to Numerical Modelling in Systems Biology
title_fullStr A Guide to Numerical Modelling in Systems Biology
title_full_unstemmed A Guide to Numerical Modelling in Systems Biology
title_sort guide to numerical modelling in systems biology
publisher Springer
publishDate 2016
url https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/59833
_version_ 1782536995691560960