Aging of the genome The dual role of the DNA in life and death
Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis...
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Ngôn ngữ: | Undetermined English |
Được phát hành: |
Oxford,New York
Oxford University Press
2007
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Thư viện lưu trữ: | Trung tâm Học liệu Trường Đại học Trà Vinh |
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LEADER | 01240nam a2200277Ia 4500 | ||
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001 | TVU_11016 | ||
008 | 210423s9999 xx 000 0 und d | ||
020 | |a 019856922X | ||
020 | |a 9780198569220 | ||
041 | |a eng | ||
082 | |a 612.8 | ||
082 | |b J33 | ||
100 | |a Vijg, Jan | ||
245 | 0 | |a Aging of the genome | |
245 | 4 | |b The dual role of the DNA in life and death | |
245 | 0 | |c Jan Vijg | |
260 | |a Oxford,New York | ||
260 | |b Oxford University Press | ||
260 | |c 2007 | ||
300 | |a x, 372 p. | ||
300 | |b ill. | ||
300 | |c 26 cm | ||
520 | |a Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead to the design of strategies to retard or reverse the deleterious effects of aging. This is particularly important in a time when we are urgently trying to unravel the genetic component of aging-related diseases | ||
650 | |a Aging; Apoptosis; Genomes | ||
700 | |a Jan Vijg | ||
980 | |a Trung tâm Học liệu Trường Đại học Trà Vinh |