Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
In this study, we have utilized a simple and sensitive colorimetric assay using unmodified gold nanoparticles to detect sulfanilamide in the presence of dopamine. The remarkable point of our analytical assay is based on the color change of AuNPs solution according to dispersion or agglomeration stat...
Đã lưu trong:
| Những tác giả chính: | , , , , , |
|---|---|
| Định dạng: | Journal article |
| Ngôn ngữ: | English |
| Được phát hành: |
Royal Society of Chemistry
2023
|
| Những chủ đề: | |
| Truy cập trực tuyến: | https://scholar.dlu.edu.vn/handle/123456789/3202 |
| Các nhãn: |
Thêm thẻ
Không có thẻ, Là người đầu tiên thẻ bản ghi này!
|
| Thư viện lưu trữ: | Thư viện Trường Đại học Đà Lạt |
|---|
| Tóm tắt: | In this study, we have utilized a simple and sensitive colorimetric assay using unmodified gold nanoparticles to detect sulfanilamide in the presence of dopamine. The remarkable point of our analytical assay is based on the color change of AuNPs solution according to dispersion or agglomeration state. Furthermore, the presence of sulfanilamide in the dopamine-coated nanogold solutions retarded the aggregation of nanoparticles leading to the delay in color change. The impacts of pH, initial concentrations of dopamine and sulfanilamide, and different interference on the colorimetric were investigated. The limitation of detection (LOD) is 0.3 µM is lower than previously reported methods for sulfanilamide determination at optimal conditions (0.1 mM of dopamine concentrations, pH 7.0, incubation time of 15 minutes). For quantitative measurement using UV-Vis spectra, good linear relationship (R2 = 0,9920 and R2 = 0,9951) between sulfanilamide concentration and absorption intensity was obtained in two range of 0.5-20 and 20-80 μM, respectively. The proposed method also showed low interference with the co-existence of some amino acids and organic chemicals in the mixture. Moreover, it was also applied to determine sulfanilamide in milk and pork samples, with good quantitative recoveries varying in the range of 97.2–101.9% and 98.3–107.7%, respectively. Increasing sulfanialmide concentration changed the color of dopamined-coated gold nanoparticles gradually from blue to red, which indicates our proposed assay unlocks a great potential in sulfaniamide analysis with the naked-eye readout. |
|---|