Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine

In this study, we have utilized a simple and sensitive colorimetric assay using unmodified gold nanoparticles to detect sulfanilamide in the presence of dopamine. The remarkable point of our analytical assay is based on the color change of AuNPs solution according to dispersion or agglomeration stat...

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Những tác giả chính: Lê, Vũ Trâm Anh, Huỳnh, Thanh Trúc, Trương, Đông Phương, Nguyễn, Đình Trung, Đinh, Văn Phúc, Cheng, Shu Hua
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Royal Society of Chemistry 2023
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Truy cập trực tuyến:https://scholar.dlu.edu.vn/handle/123456789/3202
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Thư viện lưu trữ: Thư viện Trường Đại học Đà Lạt
id oai:scholar.dlu.edu.vn:123456789-3202
record_format dspace
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic Gold nanoparticles, Sulfanilamide, Dopamine, colorimetric
spellingShingle Gold nanoparticles, Sulfanilamide, Dopamine, colorimetric
Lê, Vũ Trâm Anh
Huỳnh, Thanh Trúc
Trương, Đông Phương
Nguyễn, Đình Trung
Đinh, Văn Phúc
Cheng, Shu Hua
Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
description In this study, we have utilized a simple and sensitive colorimetric assay using unmodified gold nanoparticles to detect sulfanilamide in the presence of dopamine. The remarkable point of our analytical assay is based on the color change of AuNPs solution according to dispersion or agglomeration state. Furthermore, the presence of sulfanilamide in the dopamine-coated nanogold solutions retarded the aggregation of nanoparticles leading to the delay in color change. The impacts of pH, initial concentrations of dopamine and sulfanilamide, and different interference on the colorimetric were investigated. The limitation of detection (LOD) is 0.3 µM is lower than previously reported methods for sulfanilamide determination at optimal conditions (0.1 mM of dopamine concentrations, pH 7.0, incubation time of 15 minutes). For quantitative measurement using UV-Vis spectra, good linear relationship (R2 = 0,9920 and R2 = 0,9951) between sulfanilamide concentration and absorption intensity was obtained in two range of 0.5-20 and 20-80 μM, respectively. The proposed method also showed low interference with the co-existence of some amino acids and organic chemicals in the mixture. Moreover, it was also applied to determine sulfanilamide in milk and pork samples, with good quantitative recoveries varying in the range of 97.2–101.9% and 98.3–107.7%, respectively. Increasing sulfanialmide concentration changed the color of dopamined-coated gold nanoparticles gradually from blue to red, which indicates our proposed assay unlocks a great potential in sulfaniamide analysis with the naked-eye readout.
format Journal article
author Lê, Vũ Trâm Anh
Huỳnh, Thanh Trúc
Trương, Đông Phương
Nguyễn, Đình Trung
Đinh, Văn Phúc
Cheng, Shu Hua
author_facet Lê, Vũ Trâm Anh
Huỳnh, Thanh Trúc
Trương, Đông Phương
Nguyễn, Đình Trung
Đinh, Văn Phúc
Cheng, Shu Hua
author_sort Lê, Vũ Trâm Anh
title Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
title_short Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
title_full Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
title_fullStr Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
title_full_unstemmed Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
title_sort modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine
publisher Royal Society of Chemistry
publishDate 2023
url https://scholar.dlu.edu.vn/handle/123456789/3202
_version_ 1786708687280144384
spelling oai:scholar.dlu.edu.vn:123456789-32022023-12-28T01:54:43Z Modifier-free gold nanoparticle colorimetric sensing for detecting sulfanilamide in the presence of dopamine Lê, Vũ Trâm Anh Huỳnh, Thanh Trúc Trương, Đông Phương Nguyễn, Đình Trung Đinh, Văn Phúc Cheng, Shu Hua Gold nanoparticles, Sulfanilamide, Dopamine, colorimetric In this study, we have utilized a simple and sensitive colorimetric assay using unmodified gold nanoparticles to detect sulfanilamide in the presence of dopamine. The remarkable point of our analytical assay is based on the color change of AuNPs solution according to dispersion or agglomeration state. Furthermore, the presence of sulfanilamide in the dopamine-coated nanogold solutions retarded the aggregation of nanoparticles leading to the delay in color change. The impacts of pH, initial concentrations of dopamine and sulfanilamide, and different interference on the colorimetric were investigated. The limitation of detection (LOD) is 0.3 µM is lower than previously reported methods for sulfanilamide determination at optimal conditions (0.1 mM of dopamine concentrations, pH 7.0, incubation time of 15 minutes). For quantitative measurement using UV-Vis spectra, good linear relationship (R2 = 0,9920 and R2 = 0,9951) between sulfanilamide concentration and absorption intensity was obtained in two range of 0.5-20 and 20-80 μM, respectively. The proposed method also showed low interference with the co-existence of some amino acids and organic chemicals in the mixture. Moreover, it was also applied to determine sulfanilamide in milk and pork samples, with good quantitative recoveries varying in the range of 97.2–101.9% and 98.3–107.7%, respectively. 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