Peptides Inenergy Balance and Obesity

The prevalence of overweight and obesity has reached alarming proportions worldwide, placing this problem as one of the most relevant public health concerns. Given the current obesity epidemic, it is of paramount relevance to understand better the mechanisms underlying energy balance regulation. T...

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Tác giả chính: Frühbeck, Gema
Định dạng: Sách
Ngôn ngữ:English
Được phát hành: CABI 2014
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Truy cập trực tuyến:https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/36810
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spelling oai:scholar.dlu.edu.vn:DLU123456789-368102023-11-11T05:26:10Z Peptides Inenergy Balance and Obesity Frühbeck, Gema Balance Obesity The prevalence of overweight and obesity has reached alarming proportions worldwide, placing this problem as one of the most relevant public health concerns. Given the current obesity epidemic, it is of paramount relevance to understand better the mechanisms underlying energy balance regulation. The survival of higher organisms is dependent on the ability to procure, use and conserve energy efficiently. From an evolutionary point of view, animals feed to satisfy their immediate caloric and nutritional requirements from meal to meal, but also to allow energy and nutrients to be stored in anticipation of high energy demands or seasonal food shortages. Thus, food intake control involves the integration of external environmental cues with multiple internal physiological signals, as well as external social elements and hedonic influences. It is now evident that energy balance is achieved through highly integrated interactions involving the brain and the periphery, which are infl uenced by both genetic and environmental factors. The past decades have witnessed an explosion in the identification and characterization of the many bioactive peptides involved in energy homeostasis. In addition, most of the peptides related to body-weight control have been shown to participate in other pathophysiological manifestations, providing a molecular basis for obesity-associated diseases such as type 2 diabetes mellitus, coronary heart disease, hypertension, dyslipidaemia, stroke, osteoarthritis, sleep apnea and cancer, among others. 2014-04-02T07:05:21Z 2014-04-02T07:05:21Z 2009 Book 978 1 84593 407 1 https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/36810 en application/pdf CABI
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic Balance
Obesity
spellingShingle Balance
Obesity
Frühbeck, Gema
Peptides Inenergy Balance and Obesity
description The prevalence of overweight and obesity has reached alarming proportions worldwide, placing this problem as one of the most relevant public health concerns. Given the current obesity epidemic, it is of paramount relevance to understand better the mechanisms underlying energy balance regulation. The survival of higher organisms is dependent on the ability to procure, use and conserve energy efficiently. From an evolutionary point of view, animals feed to satisfy their immediate caloric and nutritional requirements from meal to meal, but also to allow energy and nutrients to be stored in anticipation of high energy demands or seasonal food shortages. Thus, food intake control involves the integration of external environmental cues with multiple internal physiological signals, as well as external social elements and hedonic influences. It is now evident that energy balance is achieved through highly integrated interactions involving the brain and the periphery, which are infl uenced by both genetic and environmental factors. The past decades have witnessed an explosion in the identification and characterization of the many bioactive peptides involved in energy homeostasis. In addition, most of the peptides related to body-weight control have been shown to participate in other pathophysiological manifestations, providing a molecular basis for obesity-associated diseases such as type 2 diabetes mellitus, coronary heart disease, hypertension, dyslipidaemia, stroke, osteoarthritis, sleep apnea and cancer, among others.
format Book
author Frühbeck, Gema
author_facet Frühbeck, Gema
author_sort Frühbeck, Gema
title Peptides Inenergy Balance and Obesity
title_short Peptides Inenergy Balance and Obesity
title_full Peptides Inenergy Balance and Obesity
title_fullStr Peptides Inenergy Balance and Obesity
title_full_unstemmed Peptides Inenergy Balance and Obesity
title_sort peptides inenergy balance and obesity
publisher CABI
publishDate 2014
url https://scholar.dlu.edu.vn/thuvienso/handle/DLU123456789/36810
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