The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam

Introduction: Inulins are a group of natural active polysaccharides found in ginseng and Dangshen and are mainly used in pharmaceutical preparations and functional food. The purification condition of inulin from Dangshen grown in Vietnam did not occur in previous studies. Hence, the study presente...

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Những tác giả chính: Nguyễn, Thị Thăng Long, Vũ, Ngọc Bội, Đặng, Xuân Cường
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2022
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Thư viện lưu trữ: Thư viện Trường Đại học Đà Lạt
id oai:scholar.dlu.edu.vn:123456789-975
record_format dspace
institution Thư viện Trường Đại học Đà Lạt
collection Thư viện số
language English
topic fructan; dangshen; Codonopsis javanica; purification.
spellingShingle fructan; dangshen; Codonopsis javanica; purification.
Nguyễn, Thị Thăng Long
Vũ, Ngọc Bội
Đặng, Xuân Cường
The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam
description Introduction: Inulins are a group of natural active polysaccharides found in ginseng and Dangshen and are mainly used in pharmaceutical preparations and functional food. The purification condition of inulin from Dangshen grown in Vietnam did not occur in previous studies. Hence, the study presented the content, purification degree, molecular weight, and functional group characteristics of inulin extracted from natural Dangshen roots (Codonopsis javanica) in other purification conditions. Methods: Some factors survey impact purification conditions of inulin, for example, the kinds and the concentration of the solvent, the temperature and the times of the precipitation, and the active coal impact. The objects such as the content of inulin, fructan, and crude polysaccharide, purification degree of inulin, and fructan were analyzed. Molecular weight and functional group characteristics of purification inulin extracted from Dangshen roots (Codonopsis javanica) grown in highland Lam Vien, Vietnam, were also analyzed. Results: The purification degree of inulin purified by using ethanol was higher than that using active coal, corresponding to 97.85a ± 0.84 % and 94.05 %, respectively. Inulin content was the large ratio in crude polysaccharides, exhibited via FTIR and the analysis results. Inulin and fructan were the most precipitated in ethanol, for example, 80 % and 90 % ethanol, respectively, compared to another solvent. The kind and the concentration of the solvent, the temperature and the precipitation times, and active coal impacted the content and the purification degree of inulin and fructan (p < 0.05). The precipitation of inulin and fructan in ethanol solvent was affected by the temperature. The molecular weight of inulin and fructan corresponded to 3,193 Da and 1,112,892 Da, respectively. Conclusion: Inulin of natural Dangshen roots in Lam Vien highland, Vietnam was useful for functional foods and pharmaceutics.
format Journal article
author Nguyễn, Thị Thăng Long
Vũ, Ngọc Bội
Đặng, Xuân Cường
author_facet Nguyễn, Thị Thăng Long
Vũ, Ngọc Bội
Đặng, Xuân Cường
author_sort Nguyễn, Thị Thăng Long
title The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam
title_short The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam
title_full The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam
title_fullStr The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam
title_full_unstemmed The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam
title_sort content, purification degree, and molecular weight of inulin of natural dangshen roots (codonopsis javanica) in highland lam vien, vietnam
publishDate 2022
_version_ 1768305937023500288
spelling oai:scholar.dlu.edu.vn:123456789-9752022-10-14T02:49:26Z The Content, Purification Degree, and Molecular Weight of Inulin of Natural Dangshen Roots (Codonopsis javanica) in Highland Lam Vien, Vietnam Nguyễn, Thị Thăng Long Vũ, Ngọc Bội Đặng, Xuân Cường fructan; dangshen; Codonopsis javanica; purification. Introduction: Inulins are a group of natural active polysaccharides found in ginseng and Dangshen and are mainly used in pharmaceutical preparations and functional food. The purification condition of inulin from Dangshen grown in Vietnam did not occur in previous studies. Hence, the study presented the content, purification degree, molecular weight, and functional group characteristics of inulin extracted from natural Dangshen roots (Codonopsis javanica) in other purification conditions. Methods: Some factors survey impact purification conditions of inulin, for example, the kinds and the concentration of the solvent, the temperature and the times of the precipitation, and the active coal impact. The objects such as the content of inulin, fructan, and crude polysaccharide, purification degree of inulin, and fructan were analyzed. Molecular weight and functional group characteristics of purification inulin extracted from Dangshen roots (Codonopsis javanica) grown in highland Lam Vien, Vietnam, were also analyzed. Results: The purification degree of inulin purified by using ethanol was higher than that using active coal, corresponding to 97.85a ± 0.84 % and 94.05 %, respectively. Inulin content was the large ratio in crude polysaccharides, exhibited via FTIR and the analysis results. Inulin and fructan were the most precipitated in ethanol, for example, 80 % and 90 % ethanol, respectively, compared to another solvent. The kind and the concentration of the solvent, the temperature and the precipitation times, and active coal impacted the content and the purification degree of inulin and fructan (p < 0.05). The precipitation of inulin and fructan in ethanol solvent was affected by the temperature. The molecular weight of inulin and fructan corresponded to 3,193 Da and 1,112,892 Da, respectively. Conclusion: Inulin of natural Dangshen roots in Lam Vien highland, Vietnam was useful for functional foods and pharmaceutics. 32 24 83-92 2022-09-14T09:17:16Z 2022-09-14T09:17:16Z 2020-06-15 Journal article Bài báo đăng trên tạp chí thuộc SCOPUS, bao gồm book chapter 2456-9119 10.9734/jpri/2020/v32i2430813 en Journal of Pharmaceutical Research International 2456-9119 1. Shoaib M, Shehzad A, Omar M, Rakha A, Raza H, Sharif HR, Shakeel A, Ansari A, Niazi S. Inulin: Properties, health benefits, and food applications. Carbohydr Polym. 2016;147:444-454. 2. Advax A. 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